| Title | Star As | Genre | Info |
|---|---|---|---|
| Ghosts of the Ozarks | Douglas | - | - |
| 12 Hour Shift | Jefferson | - | - |
| Blackjack: The Jackie Ryan Story | Big Jack | - | - |
| You Cannot Kill David Arquette | Himself | - | - |
| Mob Town | Ed Croswell | - | aka "Apalachin" |
| Saving Flora | Henry | - | aka "An Elephant's Journey" |
| The Wheel | Dr. Emmett Snyder | - | - |
| Bachelor Lions | David Myers | - | - |
| High Voltage | Jimmy | - | aka "Hollow Body" |
| Amanda & Jack Go Glamping | Jack Spencer | - | - |
| Chuck Hank and the San Diego Twins | Lordy P | - | - |
| On the Run | Peyton | - | - |
| Once Upon a Time in Venice | Diesel Stone | - | - |
| The Big Break | Lieutenant Ramirez | - | - |
| Casual Encounters | Louis | - | - |
| Pee-wee's Big Holiday | DJ | - | - |
| Sold | Sam | - | - |
| Truck'd Up | K.C. Ricky | TM | - |
| Bone Tomahawk | Purvis | - | - |
| Entourage | David Arquette | - | - |
| Evan's Crime | Frank Coleman | - | - |
| Orion | Savage hunter | - | - |
| The Tortoise and His Tail | Daniel | - | - |
| When the Starlight Ends | Bill | - | - |
| Field of Lost Shoes | Captain Henry A. DuPont | - | - |
| Happy Face Killer | Keith Hunter Jesperson | TM | - |
| Jake's Buccaneer Blast | Skully (voice) | TV | - |
| Just Before I Go | Albert | - | - |
| Muffin Top: A Love Story | Cameron Scott | - | - |
| The Key | Jack | - | - |
| Cleaners | Frank Barnes | TV | - |
| Cougar Town | Daniel | TV | - |
| The Cottage | Robert Mars | - | - |
| The Smart One | Buddy Cooper | TV | - |
| TRON: Uprising | Link (voice) | TV | - |
| Conception | Paul Reynolds | - | - |
| Jake and the Never Land Pirates | Skully (voice) | TV | - |
| Scream 4 | Deputy 'Dewey' Riley | - | - |
| Black Limousine | Jack | - | aka "The Land of the Astronauts" |
| The Legend of Hallowdega | Kiyash Monsef | - | - |
| Hamlet 2 | Gary | - | - |
| Nosebleed | - | - | - |
| Pushing Daisies | Randy Mann | TV | - |
| The Butler's in Love | Robert | - | - |
| In Case of Emergency | Jason Ventress | TV | - |
| The Darwin Awards | Harvey | - | - |
| The Tripper | Muff | - | - |
| Time Bomb | Mike Bookman | TM | - |
| Dirt Squirrel | Dirt Squirrel | TM | - |
| Slingshot | Ash | - | - |
| The Adventures of Shark Boy and Lava Girl in 3-D | Max's Dad | - | - |
| The Adventures of Sharkboy and Lavagirl 3-D | Max's Dad | - | - |
| The Commuters | Peter | TM | - |
| Never Die Alone | Paul | - | - |
| Riding the Bullet | George Staub | - | - |
| A Foreign Affair | Josh Adams | - | aka 2 Brothers & a Bride |
| Essentially Naked | Gordie Boggs | VI | - |
| Stealing Sinatra | Barry Keenan | - | - |
| Eight Legged Freaks | Chris McCormick | - | - |
| Happy Here and Now | Eddie | - | - |
| It's a Very Merry Muppet Christmas Movie | Daniel | TM | - |
| 3000 Miles to Graceland | Gus | - | - |
| See Spot Run | Gordon | - | - |
| Son of the Beach | Johnny Queefer | TV | - |
| SSX Tricky | Eddie Wachowski | VG | - |
| The Grey Zone | Hoffman | - | - |
| The Shrink Is In | Henry Popopolis | - | - |
| Pelswick | Mr. Jimmy | TV | aka John Callahan's Pelswick |
| Ready to Rumble | Gordie Boggs | - | - |
| Scream 3 | Dwight 'Dewey' Riley | - | - |
| Muppets From Space | Dr. Tucker | - | - |
| Never Been Kissed | Rob Geller | - | - |
| Ravenous | Pvt. Cleaves | - | aka Voraz (Mexico) |
| The Runner | Bartender | - | - |
| Free Money | Ned Jebee | - | - |
| RPM | Luke Delson | - | - |
| Dream with the Fishes | Terry | - | - |
| Life During Wartime | Tommy Hudler | - | aka The Alarmist |
| Scream 2 | Dwight 'Dewey' Riley | - | - |
| Beautiful Girls | Bobby Conway | - | - |
| Dead Man's Walk | Augustus McCrae | TV | aka Larry McMurtry's Dead Man's Walk |
| Johns | John | - | - |
| Kiss & Tell | Skippy the Forensic Man | - | - |
| Scream | Deputy Dwight 'Dewey' Riley | - | - |
| Skin and Bone | Buzz Head | - | - |
| Double Rush | Hunter | TV | aka Lickety Split |
| Fall Time | David | - | - |
| Wild Bill | Jack McCall | - | - |
| Airheads | Carter | - | - |
| Frank and Jesse | - | - | - |
| Roadracers | Dude Delaney | TM | aka Rebel Highway |
| The Road Killers | Bobby | - | aka Roadflower |
| An Ambush of Ghosts | - | - | - |
| At Home with the Webbers | Johnny Webber | TM | aka Webber's World |
| The Killing Box | Murphy | - | aka Ghost Brigade: The Killing Box |
| Buffy the Vampire Slayer | Benny Jacks | - | - |
| Cruel Doubt | Josh Duggan | TM | - |
| Halfway House | - | - | - |
| Where the Day Takes You | Rob | - | - |
| Parenthood | Tod Hawks | TV | - |
| The Outsiders | Keith 'Two-Bit' Mathews | TV | - |