| Title | Star As | Genre | Info |
|---|---|---|---|
| Four Good Days | Deb | - | - |
| Hillbilly Elegy | Mamaw | - | - |
| Sea Oak | Aunt Bernie | TM | - |
| The Wife | Joan Castleman | - | - |
| Crooked House | Lady Edith | - | - |
| Father Figures | Mrs. Reynolds | - | aka "Bastards" |
| Guardians of the Galaxy Vol. 2 | Nova Prime | - | - |
| The Wilde Wedding | Eve Wilde | - | - |
| What Happened to Monday | Nicolette Cayman | - | aka "Seven Sisters" |
| Duchess | Anna Anderson | - | - |
| The Girl with All the Gifts | Dr. Caroline Caldwell | - | aka "She Who Brings Gifts" |
| The Great Gilly Hopkins | Nonnie Hopkins | - | - |
| 5 to 7 | Arlene | - | - |
| A Classy Broad | Herself | - | - |
| Anesthesia | Marcia | - | - |
| Guardians of the Galaxy | Commander Rael | - | - |
| Low Down | Gram | - | - |
| Albert Nobbs | Albert Nobbs | - | - |
| Hoodwinked Too! Hood vs. Evil | Granny (voice) | - | - |
| Damages | Patty Hewes | TV | - |
| Evening | Mrs. Wittenborn | - | - |
| Hoodwinked | Granny | - | - |
| Nine Lives | Maggie | - | - |
| Tarzan II | Karla (voice) | VI | - |
| The Chumscrubber | Mrs. Johnson | - | - |
| Heights | Diana | - | - |
| Strip Search | - | TM | - |
| The Stepford Wives | Claire Wellington | - | - |
| Brush with Fate | Cornelia Englebrecht | TM | - |
| Le Divorce | Olivia Pace | - | - |
| The Lion in Winter | Eleanor of Aquitaine | TM | - |
| The Shield | Capt. Monica Rawling (2005-) | TV | - |
| South Pacific | Nellie Forbush | TV | aka Rodgers & Hammerstein's South Pacific |
| The Ballad of Lucy Whipple | Arvella Whipple | TM | aka California Gold |
| The Safety of Objects | Esther Gold | - | - |
| 102 Dalmatians | Cruella de Vil | - | - |
| Baby | Adult Sophie | TM | - |
| Things You Can Tell Just by Looking at Her | Dr. Elaine Keener | - | - |
| Cookie's Fortune | Camille Dixon | - | - |
| Sarah, Plain and Tall: Winter's End | Sarah Witting | TM | - |
| Tarzan | Kala | - | - |
| Air Force One | Vice President Kathryn Bennett | - | aka AFO |
| In the Gloaming | Janet | TM | - |
| Paradise Road | Adrienne Pargiter | - | - |
| 101 Dalmatians | Cruella De Vil | - | - |
| Mars Attacks! | First Lady Marsha Dale | - | - |
| Mary Reilly | Mrs. Farraday | - | - |
| Serving in Silence: The Margarethe Cammermeyer Story | Col. Margarethe Cammermeyer | TM | aka Serving in Silence |
| The Simpsons | Mona Simpson (voice) / Mother Simpson (voice) | TV | - |
| The Paper | Alicia Clark, Managing Editor New York Sun | - | - |
| Skylark | Sarah Witting | TM | aka Sarah, Plain and Tall: Skylark |
| The House of the Spirits | F�rula Trueba | - | aka �ndernes hus (Denmark) |
| Hook | Gutless | - | - |
| Meeting Venus | Karin Anderson | - | - |
| Sarah, Plain and Tall | Sarah Wheaton | TM | - |
| Hamlet | Gertrude | - | - |
| Reversal of Fortune | Sunny von Bulow/Narrator | - | - |
| She'll Take Romance | aka I'll Take Romance | TM | - |
| Immediate Family | Linda Spector | - | - |
| Dangerous Liaisons | Marquise Isabelle de Merteuil | - | - |
| Gandahar | Ambisextra | - | aka Light Years |
| Stones for Ibarra | Sara Everton | TM | - |
| Fatal Attraction | Alex Forrest | - | - |
| Jagged Edge | Teddy Barnes | - | - |
| Maxie | Jan/Maxie | - | aka Free Spirit |
| Greystoke: The Legend of Tarzan, Lord of the Apes | Jane Porter | - | - |
| Something About Amelia | Gail Bennett | TM | - |
| The Natural | Iris Gaines | - | - |
| The Stone Boy | Ruth Hillerman | - | - |
| The Big Chill | Sarah | - | - |
| The Elephant Man | Princess Alexandra | TM | aka ABC Theatre of the Month: The Elephant Man |
| The World According to Garp | Jenny Fields | - | - |
| Orphan Train | Jessica | TM | - |
| Too Far to Go | Rebecca Kuehn | TM | - |
| The Rules of the Game | Neighbor | TM | - |