| Title | Star As | Genre | Info |
|---|---|---|---|
| Here We Are: Notes for Living on Planet Earth | Narrator (voice) | - | - |
| Let Them All Talk | - | - | - |
| The Prom | Dee Dee Allen | - | - |
| Little Women (2019) | Aunt March | - | - |
| The Laundromat | Ellen Martin | - | - |
| Big Little Lies | Mary Louise Wright | TV | - |
| Mamma Mia! Here We Go Again | Donna | - | - |
| Mary Poppins Returns | Topsy | - | - |
| Five Came Back | Narrator | TV | - |
| The Post | Kay Graham | - | aka "The Papers" |
| Florence Foster Jenkins | Florence Foster Jenkins | - | - |
| Mike Nichols: American Masters | Herself | - | - |
| Starring Austin Pendleton | Herself | - | - |
| The Guardian Brothers | Narrator (voice) (version: English) | - | - |
| Master Class | Maria Callas | - | - |
| Ricki and the Flash | Ricki Rendazzo | - | - |
| Shout Gladi Gladi | Narrator (voice) | - | - |
| Suffragette | Emmeline Pankhurst | - | - |
| Into the Woods | The Witch | - | - |
| The Giver | Chief Elder | - | - |
| The Homesman | Altha Carter | - | - |
| August: Osage County | Violet Fordham | - | - |
| Hope Springs (2012) | Kay Soames | - | aka "Great Hope Springs" |
| To the Arctic 3D | Narrator (voice) | - | - |
| Web Therapy | Camilla Bowner | TV | - |
| The Iron Lady | Margaret Thatcher | - | - |
| Higglety Pigglety Pop! or There Must Be More to Life | Jennie (voice) | VI | - |
| It's Complicated | Jane | - | - |
| Julie & Julia | Julia Child | - | - |
| The Fantastic Mr. Fox | Mrs. Fox (voice) | - | - |
| Dark Matter | Joanna Silver | - | - |
| Doubt | Sister Aloysius Beauvier | - | - |
| Mamma Mia! | Donna | - | - |
| Evening | Lila Wittenborn | - | - |
| Lions for Lambs | Janine Roth | - | - |
| Rendition | Corrine Whitman | - | - |
| A Prairie Home Companion | Yolanda Johnson | - | - |
| The Ant Bully | Queen Ant (voice) | - | - |
| The Devil wears Prada | Miranda Priestly | - | - |
| Prime | Lisa Metzger | - | - |
| Lemony Snicket's A Series of Unfortunate Events | Aunt Josephine | - | aka Lemony Snicket - Rätselhafte Ereignisse (Germany) |
| The Manchurian Candidate | Eleanor Shaw | - | - |
| Angels in America | Rabbi Isidor Chemelwitz | TV | - |
| Adaptation | Susan Orlean | - | - |
| The Hours | Clarissa Vaughan | - | - |
| Artificial Intelligence: AI | Blue Mecha (voice) | - | aka A.I. Artificial Intelligence |
| Music of the Heart | Roberta Guaspari | - | - |
| Dancing at Lughnasa | Kate Mundy | - | - |
| One True Thing | Kate Gulden | - | - |
| ...First Do No Harm | Lori Reimuller | TM | - |
| Before and After | Carolyn Ryan | - | - |
| Marvin's Room | Lee | - | - |
| The Bridges of Madison County | Francesca Johnson | - | - |
| The River Wild | Gail | - | - |
| The House of the Spirits | Clara del Valle Trueba | - | aka Andernes hus (Denmark) |
| Death Becomes Her | Madeline Ashton | - | - |
| Defending Your Life | Julia | - | - |
| Postcards from the Edge | Suzanne Vale | - | - |
| Rabbit Ears: The Fisherman and His Wife | Storyteller | VI | - |
| She-Devil | Mary Fisher | - | - |
| A Cry in the Dark | Lindy Chamberlain | - | aka Evil Angels |
| The Tailor of Gloucester | Narrator | VI | - |
| Ironweed | Helen Archer | - | - |
| Rabbit Ears: The Tale of Mr. Jeremy Fisher | Storyteller (voice) | VI | - |
| Rabbit Ears: The Tale of Peter Rabbit | Storyteller (voice) | VI | - |
| Heartburn | Rachel Louise Samstat/Forman | - | - |
| Out of Africa | Karen Dinesen Blixen | - | - |
| Plenty | Susan Traherne | - | - |
| Falling in Love | Molly Gilmore | - | - |
| Little Ears: The Velveteen Rabbit | Storyteller | VI | - |
| Silkwood | Karen Silkwood | - | - |
| Alice at the Palace | Alice | TM | - |
| Sophie's Choice | Sophie | - | - |
| Still of the Night | Brooke Reynolds | - | - |
| The French Lieutenant's Woman | Sarah/Anna | - | - |
| Kramer vs. Kramer | Joanna Kramer | - | - |
| Manhattan | Jill | - | - |
| The Seduction of Joe Tynan | Karen Traynor | - | - |
| Uncommon Women... and Others | Leilah | TM | - |
| Holocaust | Inga Helms Weiss | TV | - |
| The Deer Hunter | Linda | - | - |
| Julia | Anne Marie | - | - |
| Secret Service | Edith Varney | TM | - |
| The Deadliest Season | Sharon Miller | TM | - |