| Title | Star As | Genre | Info |
|---|---|---|---|
| Blackbird (2020) | Lily | - | - |
| The Jesus Rolls | - | - | aka "Going Places" |
| Tunnels | - | - | - |
| Call Jane | - | - | - |
| The Death and Life of John F. Donovan | Grace Donovan | - | - |
| The Mustang | Prison therapist | - | aka "Mustang (2018)" |
| Butterfly in the Typewriter | Thelma | - | - |
| Still of the Night | - | - | aka "Still of Night" |
| Viper Club | Helen | - | aka "Vulture Club" |
| Viper Club | Helen | - | - |
| Whatever Makes You Happy | - | - | - |
| A Bad Moms Christmas | Carla's Mother | - | - |
| Feud | Bette Davis | TV | a.k.a. "Feud: Bette and Joan" |
| Neo Yokio | Aunt Agatha (voice) | TV | - |
| Ray Donovan | Samantha Winslow | TV | - |
| Ace the Case | Detective Dottie Wheel | - | aka "Kid Witness" |
| Mothers and Daughters | Millie | - | aka "Mothers Day" |
| Spark: A Space Tail | Bananny (voice) | - | - |
| 3 Generations | Dolly | - | aka "About Ray" |
| April and the Extraordinary World | Chimene (voice) | - | - |
| Hell & Back | Barb the Angel (voice) | - | - |
| Slipping Away | Dr. Sylvia Mansfield | - | - |
| The Meddler | Marnie Minervini | - | - |
| The Secret Life of Marilyn Monroe | Gladys Mortenson | TV | aka "Marilyn" |
| Ping Pong Summer | Randi Jammer | - | - |
| Tammy | Pearl, Tammy's grandmother | - | - |
| The Calling | Hazel Micallef | - | - |
| How to Make Money Selling Drugs | Herself | - | - |
| Irwin & Fran | Narrator | - | - |
| Mike & Molly | J.C. Small | TV | - |
| Snitch | Joanne Keeghan | - | - |
| The Big Wedding | Bebe McBride | - | aka "Gently Down the Stream" |
| The Last of Robin Hood | Florence Aadland | - | - |
| Arbitrage | Ellen Miller | - | - |
| Cloud Atlas | Madame Horrox / Older Ursula / Yusouf Suleiman / Abbess | - | - |
| Robot and Frank | Jennifer | - | - |
| That's My Boy | Mary McGarricle | - | aka "I Hate You, Dad" |
| The Big C | Joy Kleinman | TV | - |
| The Company You Keep | Sharon Solarz | - | - |
| 30 Rock | Lynn Onkman | TV | - |
| Fight for Your Right Revisited | Mother | - | - |
| Jeff Who Lives at Home | Sharon | - | - |
| The Miraculous Year | Patty Atwood | TM | - |
| Peacock | Fanny Crill | - | - |
| Solitary Man | Nancy Kalmen | - | - |
| Wall Street 2: Money Never Sleeps | Sylvia Moore | - | - |
| You Don't Know Jack | Janet Good | - | - |
| Leaves of Grass | Daisy Kincaid | - | - |
| One Million Strong | (voice) | - | - |
| The Greatest | Grace Brewer | - | - |
| The Lovely Bones | Grandma Lynn | - | - |
| Middle of Nowhere | Rhonda Berry | - | - |
| Speed Racer | Mom | - | - |
| Bernard and Doris | Doris Duke | - | - |
| Emotional Arithmetic | Melanie Lansing Winters | - | - |
| Enchanted | Queen Narissa | - | - |
| In the Valley of Elah | Joan Deerfield | - | - |
| Mr. Woodcock | Beverly Farley | - | - |
| Irresistible | Sophie | - | - |
| A Whale in Montana | - | - | - |
| Elizabethtown | Hollie Baylor | - | - |
| Romance & Cigarettes | Kitty Kane | - | - |
| The Exonerated | Sunny | TM | - |
| Alfie | Liz | - | - |
| Noel | Rose Harrison | - | - |
| Shall We Dance? | Beverly Clark | - | - |
| Children of Dune | Princess Wensicia Corrino | TV | aka Frank Herbert's Children of Dune |
| Ice Bound | Jerri Nielsen | TM | aka Ice Bound: A Woman's Survival at the South Pole |
| Igby Goes Down | Mimi Slocumb | - | - |
| Moonlight Mile | Jojo Floss | - | - |
| The Banger Sisters | Lavinia Kingsley | - | - |
| Cats & Dogs | Ivy (voice) | - | - |
| Joe Gould's Secret | Alice Neel | - | - |
| Rugrats in Paris: The Movie - Rugrats II | Coco LaBouche (voice) | - | aka Rugrats in Paris: The Movie |
| Anywhere But Here | Adele August | - | - |
| Cradle Will Rock | Margherita Sarfatti | - | - |
| Earthly Possessions | Charlotte Emory | TM | - |
| Our Friend, Martin | Mrs. Clark (voice) | VI | - |
| Illuminata | Celimene | - | aka Illuminata |
| Stepmom | Jackie Harrison | - | - |
| Twilight | Catherine Ames | - | - |
| The Need to Know | Narrator (voice) | - | - |
| James and the Giant Peach | Miss Spider (voice) | - | - |
| Dead Man Walking | Sister Helen Prejean | - | - |
| Little Women | Mrs. March | - | - |
| Safe Passage | Margaret Singer | - | - |
| The Client | Reggie Love | - | - |
| Bob Roberts | Tawna Titan | - | - |
| Light Sleeper | Ann | - | - |
| Lorenzo's Oil | Michaela Odone | - | - |
| Thelma & Louise | Louise | - | - |
| White Palace | Nora Baker | - | - |
| A Dry White Season | Melanie Bruwer | - | - |
| January Man | Christine Starkey | - | aka The January Man |
| Bull Durham | Annie Savoy | - | - |
| Sweet Hearts Dance | Sandra Boon | - | - |
| The Witches of Eastwick | Jane Spofford | - | - |
| Women of Valor | Col. Margaret Ann Jessup | TM | - |
| A.D. | Livilla | TV | aka A.D. - Anno Domini |
| Compromising Positions | Judith Singer | - | - |
| Mussolini: The Decline and Fall of Il Duce | Edda Ciano | TM | aka Mussolini and I |
| Oxbridge Blues | Natalie | TV | - |
| The Buddy System | Emily | - | - |
| The Hunger | Sarah Roberts | - | - |
| Tempest | Aretha | - | - |
| Who Am I This Time? | Helene Shaw | TM | aka American Playhouse: Who Am I This Time? |
| Atlantic City | Sally Matthews | - | aka Atlantic City |
| Loving Couples | Stephanie | - | - |
| Something Short of Paradise | Madeline Ross | - | aka Perfect Love |
| King of the Gypsies | Rose | - | - |
| Pretty Baby | Hattie | - | - |
| Checkered Flag or Crash | C.C. Wainwright | - | aka Crash |
| The Last of the Cowboys | Ginny | - | aka The Great Smokey Roadblock |
| The Other Side of Midnight | Catherine Alexander Douglas | - | - |
| Dragonfly | Chloe | - | aka One Summer Love |
| The Great Waldo Pepper | Mary Beth | - | - |
| The Rocky Horror Picture Show | Janet Weiss | - | - |
| F. Scott Fitzgerald and 'The Last of the Belles' | Ailie Calhoun | TM | - |
| June Moon | Eileen | TM | - |
| Lovin' Molly | Sarah | - | - |
| The Front Page | Peggy Grant | - | - |
| The Rimers of Eldritch | Patsy Johnson | TM | - |
| The Satan Murders | Kate | TM | - |
| The Whirlwind | - | TM | - |
| Search for Tomorrow | Sarah Fairbanks | TV | - |
| Fleur bleue | Elizabeth Hawkins | - | aka The Apprentice |
| Mortadella, La | Sally | - | aka Lady Liberty |
| A World Apart | Patrice Kahlman | TV | - |
| Joe | Melissa Compton | - | - |