| Title | Star As | Genre | Info |
|---|---|---|---|
| Pinocchio | (voice) | - | - |
| Last and First Men | Narrator (voice) | - | - |
| The French Dispatch | J. K. L. Berensen | - | - |
| The Human Voice | - | - | - |
| The Personal History of David Copperfield | Betsey Trotwood | - | - |
| Avengers: Endgame | The Ancient One | - | - |
| The Dead Don't Die | - | - | - |
| The Souvenir | Julie's mother | - | - |
| Isle of Dogs | (voice) | - | - |
| Suspiria | Madame Blanc | - | - |
| Auntie Mame | Auntie Mame | - | - |
| Okja | Nancy Mirando | - | - |
| War Machine | - | - | - |
| Doctor Strange | The Ancient One | - | - |
| Hail Caesar | Thora Tacker / Thessaly Tacker | - | - |
| Letters from Baghdad | Gertrude Bell (voice) | - | - |
| A Bigger Splash | Marianne | - | - |
| Trainwreck | Dianna | - | - |
| The Grand Budapest Hotel | Madame D. | - | - |
| David Bowie: The Stars (Are Out Tonight) | - | VI | - |
| Death for a Unicorn | Narrator (voice) | - | - |
| Only Lovers Left Alive | Eve | - | - |
| Snowpiercer | Mason | - | - |
| The Zero Theorem | Dr. Shrink-Rom | - | - |
| Moonrise Kingdom | Social Services | - | - |
| Genevieve Goes Boating | Narrator (voice) | VI | - |
| We Need to Talk About Kevin | Eva | - | - |
| The Chronicles of Narnia: The Voyage of the Dawn Treader | The White Witch | - | - |
| I Am Love | Emma Recchi | - | aka Io sono l'amore (Italy) |
| Julia | Julia | - | - |
| The Limits of Control | Blonde | - | - |
| Burn After Reading | Katie Cox | - | - |
| The Chronicles of Narnia: Prince Caspian | The White Witch | - | - |
| The Curious Case of Benjamin Button | Elizabeth Abbott | - | - |
| Michael Clayton | Karen Crowder | - | - |
| The Man from London | Camelia | - | aka Homme de Londres, L' (France) |
| Stephanie Daley | Lydie Crane | - | - |
| Broken Flowers | Penny | - | - |
| Constantine | Gabriel | - | - |
| Constantine | Gabriel (voice) | VG | - |
| The Chronicles of Narnia: The Lion, The Witch and The Wardrobe | Jadis The White Witch | - | - |
| The Somme | Narrator | TM | - |
| Thumbsucker | Audrey Cobb | - | - |
| The Statement | Annemarie Livi | - | - |
| Young Adam | Ella Gault | - | - |
| Adaptation. | Valerie Thomas | - | - |
| Teknolust | Rosetta Stone/Ruby/Marinne/Olivia | - | - |
| The Deep End | Margaret Hall | - | - |
| Vanilla Sky | Rebecca Dearborn | - | - |
| Possible Worlds | Joyce | - | aka Mondes possibles (Canada: French title) |
| The Beach | Sal | - | - |
| The War Zone | Mum | - | aka Tim Roth's The War Zone |
| Love Is the Devil: Study for a Portrait of Francis Bacon | Muriel Belcher | - | aka Love Is the Devil |
| Conceiving Ada | Ada Augusta Byron King, Countess of Lovelace | - | aka Leidenschaftliche Berechnung (Germany) |
| Female Perversions | Evelyn 'Eve' Stephens | - | aka Phantasien einer Frau (Germany) |
| Remembrance of Things Fast: True Stories Visual Lies | - | - | - |
| Blue | (voice) | - | - |
| Offene Universum, Das | Carla | TM | - |
| Wittgenstein | Lady Ottoline Morrell | - | - |
| Man to Man | Ella/Max Gericke | - | - |
| Orlando | Orlando | - | - |
| Edward II | Isabella | - | - |
| The Party: Nature Morte | Queenie | - | aka Party |
| The Garden | Madonna | - | - |
| Your Cheatin' Heart | Cissie Crouch | TV | - |
| Play Me Something | Hairdresser | - | - |
| War Requiem | Nurse | - | - |
| Andere Ende der Welt, Das | - | - | - |
| Degrees of Blindness | - | - | - |
| Ispirazione, L' | - | - | - |
| The Last of England | - | - | - |
| Aria | Young Girl (segment "Depuis le jour") | - | - |
| Friendship's Death | Friendship | - | - |
| Caravaggio | Lena | - | - |
| Egomania - Insel ohne Hoffnung | Sally | - | - |
| Zastrozzi: A Romance | Julia | TV | - |